Updated
| Feature | Holset Turbocharger HE300VG 5604175 6411519RX 5604180 for Cummins ISB 6.7L | Holset HE351VE Turbocharger for Cummins ISB 5354495 6411490 5354552 |
|---|---|---|
| See the Listing | See the Listing |
Frame Identification By OEM Stamp
Both turbochargers are Holset variable-geometry frames designed for the Cummins 6.7L ISB engine across different Ram chassis-year generations. The frame identification runs through the OEM part-number stamp on the casting of the failed turbo.
The HE300VG listing OEM identifier text reads:
The HE351VE listing OEM identifier reads:
Engineering Distinction Between The Frames
Both frames use variable-geometry vanes — moveable vanes positioned by an electronic actuator that controls boost-pressure delivery across the engine RPM band from idle through the redline at roughly 3,200 RPM on the 6.7L Cummins. The variable-geometry approach replaced the older fixed-geometry wastegate-controlled HX35 design Cummins ran on pre-2007.5 chassis with the 5.9L 24-valve engines through the 2007 model year cutover.
The engineering distinction between HE300VG and HE351VE sits in three primary areas. First, the vane sizing differs — the vane geometry is sized for the specific exhaust gas volume the 2007.5-2012 6.7L generation produces vs the slightly different exhaust profile of the 2013+ 6.7L generation after the EGR cooler revision and the urea-injection (DEF) emission system additions starting on 2013 Ram pickups. Second, the compressor wheel diameter and trim differ between the HE300VG and HE351VE frames, producing slightly different boost-vs-RPM curves at typical 25 psi peak boost on the install. Third, the chassis-side manifold mating geometry differs — the HE351VE manifold mating bolts up to the 2007.5-2012 Cummins 6.7L exhaust manifold with the 4-bolt flange pattern; the HE300VG manifold mating bolts up to the later-chassis exhaust manifold with different stud spacing and exhaust gasket geometry on 2013+ Ram applications.

Chassis-Year Fitment Identification
The chassis-year cutover between Holset HE351VE and HE300VG varies by Ram model designation, EPA emissions tier, and selected variant trim across the broader Cummins ISB platform. Identification by chassis-year guess alone is unreliable; the casting-stamp prefix on the failed Holset turbo is the binding identification check across all Cummins 6.7L applications.
The HE351VE frame typically anchors the 2007.5-2012 Cummins 6.7L Ram chassis at the 24-valve high-output generation. The HE300VG frame typically anchors selected later Ram chassis applications, often in the 2013-2018 Ram cab-chassis (2500 / 3500 / 4500 / 5500) variant where the OEM part-number chain shifted to the 5604175 / 6411519RX / 5604180 references. The exact chassis-year boundary varies — some 2013-2014 Ram 3500 dually applications still ship the HE351VE frame, while other 2012 Ram 4500 / 5500 cab-chassis applications already carry the HE300VG. The OEM stamp on the failed turbo casting is the deciding identification.
Photographing the failed turbo casting before ordering is the rebuilder-shop discipline that pays off across both Holset frames. The OEM prefix is typically stamped on the compressor housing flange (the air-intake side) or on the center cartridge mounting flange — visible without disassembly once the turbo is off the chassis after the 4 mounting bolts come out. Match the prefix against the listing OEM chain — 5354495 / 6411490 / 5354552 for HE351VE, 5604175 / 6411519RX / 5604180 for HE300VG — before ordering either frame.

Substitution Risks Between The Frames
The Holset HE300VG and HE351VE are not interchangeable on the same Cummins chassis. A chassis that originally shipped with the HE351VE frame requires the HE351VE replacement; substituting the HE300VG creates calibration misalignment, ECU code mismatch, and manifold mating issues that surface at the install bench before the chassis runs.
The calibration mismatch is the first practical install failure. The Cummins chassis ECU expects the OE Holset VGT vane geometry it was tuned for — substituting a different vane geometry from the wrong-frame replacement produces boost-pressure curves that fall outside the OEM lookup tables, triggering U010C lost-communication or other VGT diagnostic codes immediately on first start. The actuator that controls the vanes is the same electronic part across both Holset frames in some sub-variants, but the underlying vane geometry it positions is different — and the Cummins chassis ECU does not know the vane geometry changed.
The manifold mating mismatch is the second install failure on either Cummins 6.7L chassis. The exhaust manifold stud spacing and the exhaust gasket geometry differ slightly between the Holset HE300VG and HE351VE frames. A wrong-frame substitution either does not bolt up at all, or bolts up with the wrong gasket sealing surface, creating exhaust leaks at the manifold flange that compromise boost pressure across the install.
If You\'re Coming From The HE351VE Side
If you landed on the HE351VE frame first — your failed turbo casting stamps as 5354495, 6411490, or 5354552 — the HE300VG is not your replacement. The HE351VE replacement (or an HE351VE rebuilder-tier alternative) is the path forward. Cross-shopping the HE300VG here is a category error driven by the shared "Holset VGT for Cummins 6.7L" framing on both listings.
For a 2007.5-2012 Cummins 6.7L Ram chassis with a confirmed HE351VE casting stamp, the relevant cross-shop runs through the rebuilder-tier KC Turbos / Dirty Diesel Customs / BD Diesel / Fleece Performance HE351VE specialty units, the Cluster B ASDPI complete-turbo on the HE351VE / HE300VG fitment, or the Holset HE351VE Cartridge CHRA when the failed turbo\'s housings pass inspection at the rebuilder shop. The full HE351VE review and the Cluster B cross-shop comparisons linked above are the next steps for buyers making the picking decision.
If You\'re Coming From The HE300VG Side
If you landed on the Holset HE300VG frame first — your failed Cummins turbo casting stamps as 5604175, 6411519RX, or 5604180 — the HE351VE is not your replacement. The HE300VG replacement (or an HE300VG rebuilder-tier alternative) is the path forward on the later-generation Cummins ISB 6.7L Ram chassis.
For a later-generation Cummins 6.7L Ram chassis with a confirmed HE300VG casting stamp, the relevant cross-shop runs through the rebuilder-tier Fleece Performance HE300VG Cheetah variants, BD Diesel HE300VG upgrade programs, and the Cummins reman OEM HE300VG turbo programs. The full HE300VG review linked above is the next step for buyers making the picking decision.
For underlying turbocharger engineering background on the Holset variable-geometry platform both frames implement, the Wikipedia turbocharger reference documents the compressor-and-turbine architecture and the variable-geometry vane-control mechanism Cummins adopted in 2007.5 across the 6.7L ISB engine family. The TSReman Turbo University service-part catalog publishes the Holset HE300VG cross-reference (5604175 / 6411519RX / 5604180) and the HE351VE cross-reference (5354495 / 6411490 / 5354552) manifests cited by both listings. The Rotomaster understanding turbochargers reference covers the rebuilder-tier diagnostic protocol for both Holset VGT frames including the U010C lost-communication code system common across the 2007.5-2018 Cummins 6.7L Ram chassis range.
Verdict: Frame Identification Is The Decision
This is not a head-to-head competition between two products. The HE300VG and HE351VE are different Holset VGT frames serving different Cummins 6.7L Ram chassis generations on different OEM part-number chains. The buyer does not pick between them — the failed turbo\'s casting stamp picks the frame.
For a 2007.5-2012 Cummins 6.7L Ram chassis with a HE351VE casting stamp, the HE351VE replacement is the path. For a later-generation Ram chassis with a HE300VG casting stamp, the HE300VG replacement is the path. Substitution between frames is not viable. The Read Full Review links on each frame above are the next step for buyers ready to make the picking decision once the frame is identified.
Holset HE300VG path — later Cummins Ram chassis on the 5604175 chain:
Holset HE351VE path — 2007.5-2012 Cummins Ram chassis on the 5354495 chain:
Holset VGT Frame Identification Questions
- What is the difference between Holset HE300VG and HE351VE?
- Both are variable-geometry turbocharger (VGT) frames produced by Holset for the Cummins 6.7L ISB engine in Ram pickup applications, but they serve different chassis-year generations and different OEM part-number chains. The HE300VG is the later-generation Holset VGT frame matching 5604175 / 6411519RX / 5604180 OEM stamps on 2013-2018 Ram chassis fitments. The HE351VE is the earlier-generation Holset VGT frame matching the 5354495 / 6411490 / 5354552 OEM stamps on the 2007.5-2012 Cummins ISB transition window through into selected later Ram chassis. Both frames use variable-geometry vanes controlled by an electronic actuator — the engineering distinction sits in vane sizing, compressor wheel diameter, and the chassis-year fitment envelope on each Ram pickup generation.
- Which Ram chassis year takes which frame?
- The HE351VE frame anchors the 2007.5-2012 Ram 2500 / 3500 / 4500 / 5500 chassis on the Cummins 6.7L ISB engine, where the 5354495 / 6411490 / 5354552 part-number chain dominates the OEM service-part references. The HE300VG frame anchors selected later-chassis fitments (typically 2013-2018 Ram 2500 / 3500 / 4500 / 5500 cab-chassis applications) where the 5604175 / 6411519RX / 5604180 part-number chain is the OEM reference. The exact chassis-year cutover between the two frames varies by Ram model designation; the casting-stamp prefix on the failed turbo is the deciding identification check. Photograph the casting and match the OE prefix before ordering.
- Are these frames interchangeable on the same chassis?
- No. The HE300VG and HE351VE have different vane sizing, different compressor wheel diameters, and different chassis-side manifold mating geometries. A chassis that originally shipped with the HE351VE frame requires the HE351VE replacement; a chassis that originally shipped with the HE300VG frame requires the HE300VG replacement. Substitution risks calibration misalignment, ECU code mismatch, and exhaust manifold mating issues that fail at the install bench. The OEM part-number cross-reference on the listing is the binding identification — verify both the engine-side and chassis-side mating before ordering either frame.
- Which rebuilder-tier alternatives exist on each frame?
- For the HE351VE frame, rebuilder-tier alternatives include KC Turbos premium HE351VE specialty units, Dirty Diesel Customs Cummins HE351VE Holset VGT rebuilds, BD Diesel HE351VE upgrade programs, and Fleece Performance HE351VE Cheetah variants. These rebuilder-tier units carry institutional warranty depth and documented production history at the high-three-figure to mid-four-figure tier. For the HE300VG frame, rebuilder-tier alternatives include Fleece Performance HE300VG Cheetah variants, BD Diesel HE300VG upgrade programs, and the Cummins reman OEM HE300VG turbo programs. Both frames have institutional alternatives above the entry-tier Generic-brand Amazon listings represented by the two products this page compares.
For the rebuilder-tier institutional alternatives on each frame, route to the Holset HE351VE Cartridge CHRA review covering the cartridge-rebuild path on the HE351VE frame, or to the ASDPI HE351VE/HE300VG review covering the complete-turbo path across both frame generations on 2008-2010 Cummins ISB 6.7L applications.